Puppies start signs 3 hours to 10 days after administering.
- Fever.
- Sluggishness.
- Loss of appetite.
- Facial or paw swelling and/or hives.
- Vomiting.
- Diarrhea.
- Pain or swelling around the injection site.
- Collapse, difficulty breathing, and seizures (anaphylactic shock)
Additional signs we have encountered related to the Adenovirus Type 2 vaccine.
- Swelling specifically in the muzzle, around the eyes, and pads of the feet
- Drooling
- Consistent drinking
- Belly bloating
- Rear legs stuck in the stretched position
- Blood in the stools
- Uncontrollable shaking
- Pupils not dilating
- Eyes changing to a grey color and can turn the eye white. (friends puppy)
- Temperatures after anaphylactic shock from 104 – 107 degrees
- Death
What we did to help make the puppies through the reaction.
- Submerged the puppies in cold water until fever went down to 102
- Sub Q fluids
- Keep allowing and helping the puppy drink electrolyte water
- Checking the temperature hourly
- Do not keep moving your puppy. The muscles tense so much their body will be very sore
- Rear legs stuck in the stretched position
